The Molecular Grand Round – Initial Experience Sharing on NGS-Guided Oncology Practice” was held on May 16th, 2018. The event was co-organized by the Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong and Gleneagles HK Hospital, and sponsored by ACT Genomics. The Molecular Grand Round was very successful, and we received many positive feedbacks. The face-to-face case sharing experience on molecular genetics and genomics was one of its kind in Hong Kong and even worldwide. It reinforced the significance of using NGS as a diagnostic technique for precision medicine in oncology. The enthusiastic audience and speakers are anticipating for the next Molecular Grand Round. This opportunity allows us to further promote precision oncology to the Hong Kong medical community.